Making a decision: to stay or move

Glucose induces delocalization of a flagellar biosynthesis protein from the flagellated pole
 
Making a right decision to stay or move is critical for survival in a changing environment. Here we identify a novel mechanism for glucose-dependent on-off switching of flagellar synthesis in Vibrio vulnificus: When enzyme IIA^Glc of the bacterial PEP:carbohydrate phosphotransferase system is dephosphorylated in the presence glucose, it delocalizes a protein required for flagellar biosynthesis from the flagellated pole. This leads to a loss of motility and enables bacteria to stay in a favorable habitat.

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